Intra-Cytoplasmic Sperm Injection (ICSI)

ICSI is a fertilisation method that involves choosing a single sperm and injecting it into a mature egg using a very fine needle under microscopic control. ICSI assists the sperm to achieve fertilisation and is the recommended treatment for Male Factor Infertility.

What is ICSI?

ICSI assists the sperm to achieve fertilisation and is the recommended treatment for Male Factor Infertility.

When is ICSI recommended?

ICSI treatment is recommended in the following cases:

  • Low sperm parameters (count, motility abnormal forms)or the presence of anti-sperm antibodies within the sample.
  • No sperm in the ejaculate due to previous vasectomy, blockage or absence of the Vas Deferens, early testicular failure or problems with ejaculation. Surgical sperm retrieval known as PESA and/or TESE, will be required in those cases.
  • Previous low fertilisation rate or failure to fertilise with conventional IVF.
  • When the female partner is over the age of 40, the age-related thickening of the shell surrounding the egg may make it harder for sperm to naturally penetrate.

Following the ICSI procedure, the injected eggs are incubated overnight and assessed the following morning by one of the embryology team for evidence of fertilisation. The average fertilisation rate following ICSI is similar to IVF with 60-70% of injected eggs fertilising normally. ICSI is the only treatment option for sperm samples that have been surgically retrieved.

Preparation for ICSI

Please note that the only difference between ICSI and conventional IVF is the laboratory procedure performed once the eggs and sperm have been obtained. The preparation for the female patient for ICSI is identical to that of IVF. The woman will be required to undergo viral screening, drug stimulation, ultrasound monitoring and egg collection as for IVF.

The embryology team will be more than happy to assist you with any questions you may have regarding whether IVF or ICSI is the best treatment for you.

After the procedure

Your fertilised eggs are monitored closely and our embryology team will assess the best day to transfer the developing embryo(s) into the womb.

You can be assured of the best possible treatment throughout these procedures and of our continued support and care.

Our team of embryologists has been recognised by GameteExpert 2014 as one of the very best in Europe for their expertise in assessing embryos and sperm.

We are consistently one of the top performing fertility clinics in the UK.

Our team of embryologists came third out of 78 top performing laboratories for skills in embryo assessment in the GameteExperts in 2014. You can read more here.



Treatment Cost*  
Treatment Cost Average Cost (£)
New consultation – heterosexual and same-sex couples £300
New consultation – single lady £250
Female screening £130 per person
Pipelle £195
Saline Infusion Sonography and Pipelle £450
Counselling Free  
HFEA fee – IVF/ICSI £80  
IVF treatment with ICSI – Intra cytoplasmic sperm injection £4,125


Medication – based on an average length of stimulation £1,500 – £3,000
Drugs based on x 12 inj @ 150iu per day Drugs based on x 12 inj @ 450iu per day
Suprecur (3 bottles) £93 Suprecur (3 bottles) £93
Cetrotide (8 vials) £240 Cetrotide (8 vials) £240
Stimulation x 12 days £744 Stimulation x 12 days £2,232
Cyclogest (2 boxes) £48 Cyclogest (2 boxes) £48
Doxycycline (1box) £8 Doxycycline (1box) £8
Gonasi x 2 / Ovitrelle £45 Gonasi x 2 / Ovitrelle £45
Sub total £1,178 Sub total £2,666


Treatment Cost*  
Extra medication costs, if needed
(for 2 weeks until pregnancy test).
Average Cost (£)
Aspirin 75 mg daily
(1 box with 56 tablets)
Prednisolone 20 mg daily
( 2 boxes of 28 tablets each)
Clexane 20mg daily
(2 boxes of 10 injections each)
Prontogest 100 mg daily
( 5 boxes with 3 ampoules each)
Lubion 25mg daily
(2 boxes with 7 vials each)
Pregnancy scan £175
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